Can you help me with this question:

Estrogens are small hydrophobic lipid hormones that promote cell division and the development of reproductive structures in mammals. Estrogens passively diffuse across the plasma membrane and bind to their receptor proteins in the cytoplasm of target cells.

(a) Describe ONE characteristic of the plasma membrane that allows estrogens to passively cross the membrane.

(b) In a laboratory experiment, a researcher generates antibodies that bind to purified estrogen receptors extracted from cells. The researcher uses the antibodies in an attempt to treat estrogen-dependent cancers but finds that the treatment is ineffective. Explain the ineffectiveness of the antibodies for treating estrogen-dependent cancers.

A) The semi-permeability of the plasma membrane is the characteristic that allows estrogens to passively cross the membrane through diffusion.

B) Antibodies are unable to cross the plasma membrane of the cellls. The receptor proteins are located within cytoplasm of the cell , because of this using antibodies to block the receptor would be useless as the antibodies are too large to enter the cell and bind to the receptors.