One more question for you please
What is the relative acidity of the most acidic hydrogen in each of the following:
Acidity means looking at the stability of the conjugate bases, but first we should identify which atom is going to become negative by locating the most acidic H in each case. In i we have an alcohol OH, ii is also an alcohol, but with electronegative F atoms present and iii is an amine NH. So the negative charge will be on these heteroatoms. O is more electronegative than N meaning the O will stablise the anion more, so the alkoxide (from ROH) is more stable than the amide ion (from RNH2). The F atoms in ii will stabilise the conjugate base due to the electron withdrawing nature of the electronegative F atoms. So for the acidity, ii > i > iii